Barrier function of the skin and the role of fat-soluble vitamins in the correction of its disorders

The main function of the skin is to protect body from negative environmental influences. physical barrier permeability mainly represented by stratum corneum; however, other layers epidermis and dermis are its important components. mechanical strength provided intercellular contacts in structural proteins dermis. chemical-biological includes lipids, acids, natural moisturizing factor antimicrobial peptides. Mucosal immunity system creates a against infection. microflora healthy counteracts colonization pathogens vital for immune functions. Physiological processes closely related. A violation one them often leads formation whole cascade pathological reactions affecting all links protection. Vitamins A, D E used correct impaired skin. most pronounced effect vitamin (retinol palmitate) proliferation epidermal cells synthesis extracellular matrix structures dermis; (cholecalciferol) regulation differentiation suppression excessive keratinocytes; (tocopherol acetate) antioxidant effect. combined use these vitamins composition RadevitActive ointment affects elements protection dermis: strengthens corneum dermis, stabilizes chemical protection, including prevents penetration foreign substances microorganisms, reduces transepidermal loss water electrolytes, damaging UV, increases